Phoneutria nigriventer toxin-3
Broad-spectrum calcium channel blocker / From Wikipedia, the free encyclopedia
Phoneutria nigriventer toxin-3 is more commonly referred to as PhTx3.
The PhTx3 neurotoxin is a broad-spectrum calcium channel blocker that inhibits glutamate release, calcium uptake and also glutamate uptake in synaptosomes.[1] Currently, it is known to naturally occur only in the venom of the spider Phoneutria nigriventer, also known as the Brazilian Wandering spider.