Phosphoserine transaminase
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Phosphoserine transaminase (EC 2.6.1.52, PSAT, phosphoserine aminotransferase, 3-phosphoserine aminotransferase, hydroxypyruvic phosphate-glutamic transaminase, L-phosphoserine aminotransferase, phosphohydroxypyruvate transaminase, phosphohydroxypyruvic-glutamic transaminase, 3-O-phospho-L-serine:2-oxoglutarate aminotransferase, SerC, PdxC, 3PHP transaminase) is an enzyme with systematic name O-phospho-L-serine:2-oxoglutarate aminotransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- (1) O-phospho-L-serine + 2-oxoglutarate 3-phosphonooxypyruvate + L-glutamate
- (2) 4-phosphonooxy-L-threonine + 2-oxoglutarate (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate
Quick Facts Identifiers, EC no. ...
Phosphoserine transaminase | |||||||||
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Identifiers | |||||||||
EC no. | 2.6.1.52 | ||||||||
CAS no. | 9030-90-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This enzyme is a pyridoxal-phosphate protein.
- Drewke C, Klein M, Clade D, Arenz A, Müller R, Leistner E (July 1996). "4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis". FEBS Letters. 390 (2): 179–82. doi:10.1016/0014-5793(96)00652-7. PMID 8706854.
- Zhao G, Winkler ME (January 1996). "4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12". FEMS Microbiology Letters. 135 (2–3): 275–80. doi:10.1111/j.1574-6968.1996.tb08001.x. PMID 8595869.
- Phosphoserine+transaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)