Thymidine phosphorylase
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Thymidine phosphorylase (EC 2.4.2.4) is an enzyme that is encoded by the TYMP gene and catalyzes the reaction:
- thymidine + phosphate thymine + 2-deoxy-alpha-D-ribose 1-phosphate
This article may be too technical for most readers to understand. (November 2017) |
Quick Facts Identifiers, EC no. ...
Thymidine phosphorylase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.2.4 | ||||||||
CAS no. | 9030-23-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thymidine phosphorylase is involved in purine metabolism, pyrimidine metabolism, and other metabolic pathways. Variations in thymidine phosphorylase and the TYMP gene that encode it are associated with mitochondrial neurogastrointestinal encephalopathy (MNGIE) syndrome and bladder cancer.