Plummer–Vinson syndrome
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Plummer–Vinson syndrome (known as Paterson–Kelly[1] or Paterson–Brown-Kelly syndrome in the UK[2]) is a rare disease characterized by difficulty swallowing, iron-deficiency anemia, glossitis, cheilosis and esophageal webs.[1] Treatment with iron supplementation and mechanical widening of the esophagus generally provides an excellent outcome.
Plummer–Vinson syndrome | |
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Other names |
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Angular stomatitis | |
Specialty | Gastroenterology |
While exact data about the epidemiology is unknown, this syndrome has become extremely rare. The reduction in the prevalence of Plummer–Vinson syndrome has been hypothesized to be the result of improvements in nutritional status and availability in countries where the syndrome was previously described.[1] It generally occurs in perimenopausal women. Its identification and follow-up is considered relevant due to increased risk of squamous cell carcinomas of the esophagus and pharynx.[1]