Positron emission mammography
Imaging procedure used to detect breast cancer / From Wikipedia, the free encyclopedia
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Positron emission mammography (PEM) is a nuclear medicine imaging modality used to detect or characterise breast cancer.[1] Mammography typically refers to x-ray imaging of the breast, while PEM uses an injected positron emitting isotope and a dedicated scanner to locate breast tumors. Scintimammography is another nuclear medicine breast imaging technique, however it is performed using a gamma camera. Breasts can be imaged on standard whole-body PET scanners, however dedicated PEM scanners offer advantages including improved resolution.[2][3]
PEM is not recommended for routine use or for breast cancer screening, in part due to higher radiation dose compared to other modalities.[4] Compared to breast MRI, PEM offers higher specificity.[5] Specific indications can include "high-risk patients with masses > 2 cm or aggressive malignancy and serum tumor marker elevation".[6][7] 18F-FDG is the most common radiopharmaceutical used for PEM.[8]