Rhodopsin kinase
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Rhodopsin kinase (EC 2.7.11.14, rod opsin kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GRK1, opsin kinase, opsin kinase (phosphorylating), rhodopsin kinase (phosphorylating), RK, STK14) is a serine/threonine-specific protein kinase involved in phototransduction.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction:
- ATP + rhodopsin ADP + phospho-rhodopsin
Quick Facts G protein-coupled receptor kinase 1, Identifiers ...
G protein-coupled receptor kinase 1 | |||||||
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Identifiers | |||||||
Symbol | GRK1 | ||||||
Alt. symbols | RHOK | ||||||
NCBI gene | 6011 | ||||||
HGNC | 10013 | ||||||
OMIM | 180381 | ||||||
RefSeq | NM_002929 | ||||||
UniProt | Q15835 | ||||||
Other data | |||||||
EC number | 2.7.11.14 | ||||||
Locus | Chr. 13 q34 | ||||||
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Mutations in rhodopsin kinase are associated with a form of night blindness called Oguchi disease.[9]