Sulfate transporter
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about SLC26A2?
Summarize this article for a 10 year old
The sulfate transporter is a solute carrier family protein that in humans is encoded by the SLC26A2 gene.[5] SLC26A2 is also called the diastrophic dysplasia sulfate transporter (DTDST), and was first described by Hästbacka et al. in 1994.[5] A defect in sulfate activation described by Superti-Furga in achondrogenesis type 1B[6] was subsequently also found to be caused by genetic variants in the sulfate transporter gene.[7] This sulfate (SO42−) transporter also accepts chloride, hydroxyl ions (OH−), and oxalate as substrates.[8][9] SLC26A2 is expressed at high levels in developing and mature cartilage, as well as being expressed in lung, placenta, colon, kidney, pancreas and testis.[10][11]