Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
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Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) (EC 1.1.1.325) is an enzyme with systematic name L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- (1) L-threo-7,8-dihydrobiopterin + NADP+ sepiapterin + NADPH + H+
- (2) L-threo-tetrahydrobiopterin + 2 NADP+ 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H+
Quick Facts Identifiers, EC no. ...
Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.325 | ||||||||
CAS no. | 9059-48-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This bacterial (Chlorobium tepidum) enzyme catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP.