Small-cell carcinoma
Type of malignant cancer / From Wikipedia, the free encyclopedia
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Small-cell carcinoma is a type of highly malignant cancer that most commonly arises within the lung,[1] although it can occasionally arise in other body sites, such as the cervix,[2] prostate,[3] and gastrointestinal tract. Compared to non-small cell carcinoma, small cell carcinoma is more aggressive, with a shorter doubling time, higher growth fraction, and earlier development of metastases.[4]
Small-cell carcinoma | |
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Other names | Small-cell lung cancer, Oat-cell carcinoma |
Micrograph of a small-cell carcinoma of the lung showing cells with nuclear moulding, minimal amount of cytoplasm and stippled chromatin. FNA specimen. Field stain. | |
Specialty | Oncology |
Extensive stage small cell lung cancer (SCLC) is classified as a rare disorder.[5] Ten-year relative survival rate (combined limited and extensive SCLC) is 3.5% (4.3% for women, 2.8% for men).[6] Survival can be higher or lower based on a combination of factors including stage, age, sex and race.[7] While all lung cancers are associated with tobacco smoking, SCLC is very strongly associated with tobacco smoking.[4]