T-Coffee
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T-Coffee (Tree-based Consistency Objective Function for Alignment Evaluation) is a multiple sequence alignment software using a progressive approach.[1] It generates a library of pairwise alignments to guide the multiple sequence alignment. It can also combine multiple sequences alignments obtained previously and in the latest versions can use structural information from PDB files (3D-Coffee). It has advanced features to evaluate the quality of the alignments and some capacity for identifying occurrence of motifs (Mocca). It produces alignment in the aln format (Clustal) by default, but can also produce PIR, MSF, and FASTA format. The most common input formats are supported (FASTA, PIR).
This article may have confusing or ambiguous abbreviations. (April 2011) |
Quick Facts Developer(s), Stable release ...
Developer(s) | Cédric Notredame, Centro de Regulacio Genomica (CRG) - Barcelona |
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Stable release | 13.45.0.4846264
/ 15 October 2020; 3 years ago (2020-10-15) |
Preview release | 13.45.33.7d7e789
/ 23 December 2020; 3 years ago (2020-12-23) |
Repository | |
Operating system | UNIX, Linux, MS-Windows, Mac OS X |
Type | Bioinformatics tool |
Licence | GPL |
Website | www |
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