Tiapride
Antipsychotic medication / From Wikipedia, the free encyclopedia
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Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.[2] A derivative of benzamide, tiapride is chemically and functionally similar to other benzamide antipsychotics such as sulpiride and amisulpride known for their dopamine antagonist effects.
Quick Facts Clinical data, Trade names ...
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Trade names | Tiapridal |
Routes of administration | Oral (tablets), IM, IV |
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Bioavailability | ~75% (oral) (Tmax = 1 hour) |
Protein binding | Negligible |
Elimination half-life | 2.9–3.6 hours |
Excretion | Urine (70% as unchanged tiapride) |
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ECHA InfoCard | 100.051.717 |
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Formula | C15H24N2O4S |
Molar mass | 328.43 g·mol−1 |
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