Transcription factor II A
Nuclear protein / From Wikipedia, the free encyclopedia
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Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA.[1] TFIIA is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a complex composed of the TATA binding protein TBP and TBP-associated factors (TAFs), as well as the factors TFIIB, TFIIE, TFIIF, and TFIIH. Together, these factors are responsible for promoter recognition and the formation of a transcription preinitiation complex (PIC) capable of initiating RNA synthesis from a DNA template.
Quick Facts general transcription factor IIA, 1, 19/37kDa, Identifiers ...
general transcription factor IIA, 1, 19/37kDa | |||||||
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Identifiers | |||||||
Symbol | GTF2A1 | ||||||
NCBI gene | 2957 | ||||||
HGNC | 4646 | ||||||
OMIM | 600520 | ||||||
RefSeq | NM_201595 | ||||||
UniProt | P52655 | ||||||
Other data | |||||||
Locus | Chr. 14 q31 | ||||||
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Quick Facts general transcription factor IIA, 2, 12kDa, Identifiers ...
general transcription factor IIA, 2, 12kDa | |||||||
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Identifiers | |||||||
Symbol | GTF2A2 | ||||||
NCBI gene | 2958 | ||||||
HGNC | 4647 | ||||||
OMIM | 600519 | ||||||
RefSeq | NM_004492 | ||||||
UniProt | P52657 | ||||||
Other data | |||||||
Locus | Chr. 15 q21.3 | ||||||
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