Trimebutine
Chemical compound / From Wikipedia, the free encyclopedia
Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.[1] It is used for the treatment of irritable bowel syndrome and other gastrointestinal disorders.
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Trade names | Debridat, Recutin, Polybutin, others |
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ECHA InfoCard | 100.049.354 |
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Formula | C22H29NO5 |
Molar mass | 387.476 g·mol−1 |
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The major product from drug metabolism of trimebutine in human beings is nortrimebutine,[2] which comes from removal of one of the methyl groups attached to the nitrogen atom. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract.[3]
Both trimebutine and its metabolite[citation needed] are commercially available.