Trovafloxacin
Antibiotic / From Wikipedia, the free encyclopedia
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Trovafloxacin (sold as Trovan by Pfizer and Turvel by Laboratorios Almirall) is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.[1] It was withdrawn from the market due to the risk of hepatotoxicity. It had better Gram-positive bacterial coverage but less Gram-negative coverage than the previous fluoroquinolones.
Quick Facts Clinical data, AHFS/Drugs.com ...
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AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a605016 |
Routes of administration | Oral, intravenous |
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Formula | C20H15F3N4O3 |
Molar mass | 416.360 g·mol−1 |
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