User:Hifzasakhi/Cycloserine
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Cycloserine is a second-line drug used in the treatment of tuberculosis. It is restricted for extremely drug resistant strains. Interestingly, it was found that this drug can also penetrate into the central nervous system (CNS). [1] Since then, cycloserine has also been found to aid in the treatment of various neurological disorders, due to its effects as a selective partial agonist of the N-methyl-D-aspartate (NMDA) glutamatergic receptors. Specifically, it affects the glycine-binding sites which are important for opening NMDA channels. [1] [2]. Cycloserine is stable under basic conditions but breaks down into serine and hydroylamine under acidic conditions.[3] .