User:Mr. Ibrahem/Flunitrazepam
Chemical compound / From Wikipedia, the free encyclopedia
Flunitrazepam, also known as Rohypnol among other names, is a benzodiazepine which has been used to treat trouble sleeping and to assist with anesthesia.[3][4] It is not an initially recommended treatment and is only recommended for short-term use.[3][5]
Clinical data | |
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Pronunciation | /ˌfluːnɪˈtræzɪpæm/ |
Trade names | Rohypnol, others[1] |
Other names | Circles, Forget Me Pill, La Rocha, Lunch Money Drug, Mexican Valium[2] |
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Addiction liability | High[3] |
Routes of administration | By mouth |
Drug class | Benzodiazepine[3] |
Legal status | |
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Pharmacokinetic data | |
Bioavailability | 64–77% (by mouth) 50% (suppository) |
Metabolism | Liver |
Metabolites | 7-aminoflunitrazepam, desmethylflunitrazepam and 3-hydroxydesmethylflunitrazepam |
Onset of action | Rapid[3] |
Elimination half-life | 18–26 hours |
Excretion | Kidney |
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Chemical and physical data | |
Formula | C16H12FN3O3 |
Molar mass | 313.288 g·mol−1 |
3D model (JSmol) | |
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Side effects include a risk of abuse, night time eating, confusion, and withdrawal symptoms if stopped suddenly after long term use.[3][6][7] In high doses decreased efforts to breath and death may result.[7] After prolonged use the medication needs to be slowly stopped.[7]
Flunitrazepam was patented in 1962 and came into medical use in 1974.[8] It not legally available in the United States, Australia, and New Zealand and is restricted in parts of Europe.[6] It has been referred to as a date rape drug,[9][10] though the percentage of reported rape cases in which it is involved is small.[11]