User:Organic Chemist 19/sandbox
From Wikipedia, the free encyclopedia
The Suzuki reaction is the organic reaction that is classified as a coupling reaction where the coupling partners are a boronic acid with a halide catalyzed by a palladium(0) complex[1][2][3]. It was first published in 1979 by Akira Suzuki and he shared the 2010 Nobel Prize in Chemistry with Richard F. Heck and Ei-ichi Negishi for their effort for discovery and development of palladium-catalyzed cross couplings in organic synthesis.[4]. In many publications this reaction also goes by the name Suzuki–Miyaura reaction and is also referred to as the "Suzuki Coupling". It is widely used to synthesize poly-olefins, styrenes, and substituted biphenyls. Several reviews have been published describing advancements and the development of the Suzuki Reaction.[5] [6][7]. The general scheme for the Suzuki reaction is shown below where you form a carbon-carbon single bond by coupling a organoboron species (R1-BY2) with a halide (R2-X) using a palladium catalyst and a base.
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