Villin-1
Actin-binding protein / From Wikipedia, the free encyclopedia
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Villin-1 is a 92.5 kDa tissue-specific actin-binding protein associated with the actin core bundle of the brush border.[1] Villin-1 is encoded by the VIL1 gene. Villin-1 contains multiple gelsolin-like domains capped by a small (8.5 kDa) "headpiece" at the C-terminus consisting of a fast and independently folding three-helix bundle that is stabilized by hydrophobic interactions.[2] The headpiece domain is a commonly studied protein in molecular dynamics due to its small size and fast folding kinetics and short primary sequence.[3][4]
Quick Facts Identifiers, Symbol ...
Villin-1 | |||||||
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Identifiers | |||||||
Symbol | VIL1 | ||||||
Alt. symbols | VIL | ||||||
NCBI gene | 7429 | ||||||
HGNC | 12690 | ||||||
OMIM | 193040 | ||||||
RefSeq | NM_007127 | ||||||
UniProt | P09327 | ||||||
Other data | |||||||
Locus | Chr. 2 q35-q36 | ||||||
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Quick Facts Identifiers, Symbol ...
villin 2 (ezrin) | |||||||
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Identifiers | |||||||
Symbol | VIL2 | ||||||
NCBI gene | 7430 | ||||||
HGNC | 12691 | ||||||
OMIM | 123900 | ||||||
RefSeq | NM_003379 | ||||||
UniProt | P15311 | ||||||
Other data | |||||||
Locus | Chr. 6 q22-q27 | ||||||
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