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Aminopropionitrile
Chemical compound From Wikipedia, the free encyclopedia
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Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is a colourless liquid. The compound occurs naturally and is of interest in the biomedical community.
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Biochemical and medical occurrence
BAPN is the toxic constituent of peas from Lathyrus plants, e.g., Lathyrus odoratus.[3] Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities."[4] It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism.
It is an antirheumatic agent in veterinary medicine.
It has attracted interest as an anticancer agent.[5]
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Production
Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.[6]
See also
References
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