Oxofluoxymesterone

Oxofluoxymesterone (developmental code name U-6596), or ketofluoxymesterone, is an androgen and anabolic steroid (AAS) which was never marketed.^[1][2][3] It was assessed in the treatment of breast cancer in women in the 1970s and showed effectiveness similar to that of other AAS.^[1][2][4] The drug is the 11-dehydrogenated analogue and a metabolite of fluoxymesterone.^[1][2][3][5]

Oxofluoxymesterone

Clinical data
Other names	U-6596; Ketofluoxymesterone; 11-Oxofluoxymesterone; 11-Ketofluoxymesterone; 9α-Fluoro-11-oxo-17α-methyltestosterone; 9α-Fluoro-17α-methylandrost-4-en-17β-ol-3,11-dione
Routes of administration	By mouth
Drug class	Androgen; Anabolic steroid
Identifiers
IUPAC name (8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
CAS Number	465-69-0
PubChem CID	10065
ChemSpider	9669
UNII	0083BRI2A7
KEGG	C14621
ChEBI	CHEBI:34510
ChEMBL	ChEMBL406406
CompTox Dashboard (EPA)	DTXSID90196860
Chemical and physical data
Formula	C20H27FO3
Molar mass	334.431 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2(C(=O)C[C@]4([C@H]3CC[C@]4(C)O)C)F
InChI InChI=1S/C20H27FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-15,24H,4-9,11H2,1-3H3/t14-,15-,17-,18-,19-,20-/m0/s1 Key:YUMWOIMGKYOLOA-MWTXUKJESA-N

See also

• Dihydrofluoxymesterone