12-hydroxydihydrochelirubine 12-O-methyltransferase

In enzymology, a 12-hydroxydihydrochelirubine 12-O-methyltransferase (EC 2.1.1.120) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + dihydromacarpine

12-hydroxydihydrochelirubine 12-O-methyltransferase
Identifiers
EC no.	2.1.1.120
CAS no.	158736-40-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are S-adenosyl methionine and 12-hydroxydihydrochelirubine, whereas its two products are S-adenosylhomocysteine and dihydromacarpine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.