2'-N-acetylparomamine deacetylase

2'-N-acetylparomamine deacetylase (EC 3.5.1.112, btrD (gene), neoL (gene), kanN (gene)) is an enzyme with systematic name 2'-N-acetylparomamine hydrolase (acetate-forming).^[1][2] This enzyme catalyses the following chemical reaction

2'-N-acetylparomamine + H₂O ${\displaystyle \rightleftharpoons }$ paromamine + acetate

2'-N-acetylparomamine deacetylase
Identifiers
EC no.	3.5.1.112
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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This enzyme takes part in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin.