2,3-dimethylmalate lyase

The enzyme 2,3-dimethylmalate lyase (EC 4.1.3.32) catalyzes the chemical reaction

(2R,3S)-2,3-dimethylmalate ${\displaystyle \rightleftharpoons }$ propanoate + pyruvate

2,3-dimethylmalate lyase
Identifiers
EC no.	4.1.3.32
CAS no.	73562-28-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming). Other names in common use include 2,3-dimethylmalate pyruvate-lyase, and (2R,3S)-2,3-dimethylmalate pyruvate-lyase. This enzyme participates in c5-branched dibasic acid metabolism.