2-Amino-4-deoxychorismate synthase

2-amino-4-deoxychorismate synthase (EC 2.6.1.86, ADIC synthase, 2-amino-2-deoxyisochorismate synthase, SgcD) is an enzyme with systematic name (2S)-2-amino-4-deoxychorismate:2-oxoglutarate aminotransferase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

(2S)-2-amino-4-deoxychorismate + L-glutamate ${\displaystyle \rightleftharpoons }$ chorismate + L-glutamine

2-amino-4-deoxychorismate synthase
Identifiers
EC no.	2.6.1.86
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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This enzyme requires Mg²⁺. The reaction occurs in the reverse direction.