2-Aminomuconate deaminase

"amnd" redirects here. For the play, see A Midsummer Night's Dream.

In enzymology, 2-aminomuconate deaminase (EC 3.5.99.5) (also known as amnd) is an enzyme that catalyzes the chemical reaction

2-aminomuconate + H₂O ${\displaystyle \rightleftharpoons }$ 4-oxalocrotonate + NH₃

2-aminomuconate deaminase
Identifiers
EC no.	3.5.99.5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are 2-aminomuconate and H₂O, whereas its two products are 4-oxalocrotonate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 2-aminomuconate aminohydrolase. This enzyme participates in tryptophan metabolism.