2-dehydro-3-deoxy-D-pentonate aldolase

The enzyme 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) catalyzes the chemical reaction

2-dehydro-3-deoxy-Dpentonate ${\displaystyle \rightleftharpoons }$ pyruvate + glycolaldehyde

2-dehydro-3-deoxy-D-pentonate aldolase
Identifiers
EC no.	4.1.2.28
CAS no.	55326-36-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-D-pentonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions.