2-dehydropantoate aldolase

The enzyme 2-dehydropantoate aldolase (EC 4.1.2.12) catalyzes the chemical reaction:

2-dehydropantoate ${\displaystyle \rightleftharpoons }$ 3-methyl-2-oxobutanoate + formaldehyde

2-dehydropantoate aldolase
Identifiers
EC no.	4.1.2.12
CAS no.	9024-51-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming). Other names in common use include ketopantoaldolase, and 2-dehydropantoate formaldehyde-lyase.