2-enoate reductase

In enzymology, a 2-enoate reductase (EC 1.3.1.31) is an enzyme that catalyzes the chemical reaction

butanoate + NAD⁺ ${\displaystyle \rightleftharpoons }$ 2-butenoate + NADH + H⁺

2-enoate reductase
Identifiers
EC no.	1.3.1.31
CAS no.	70712-51-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are butanoate and NAD⁺, whereas its 3 products are 2-butenoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is butanoate:NAD+ Delta2-oxidoreductase. This enzyme is also called enoate reductase. This enzyme participates in phenylalanine metabolism. It has 4 cofactors: FAD, Iron, Sulfur, and Iron-sulfur.