2-hexadecenal reductase

In enzymology, a 2-hexadecenal reductase (EC 1.3.1.27) is an enzyme that catalyzes the chemical reaction

hexadecanal + NADP⁺ ${\displaystyle \rightleftharpoons }$ 2-trans-hexadecenal + NADPH + H⁺

2-hexadecenal reductase
Identifiers
EC no.	1.3.1.27
CAS no.	52227-95-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are hexadecanal and NADP⁺, whereas its 3 products are 2-trans-hexadecenal, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hexadecanal:NADP+ Delta2-oxidoreductase. Other names in common use include 2-alkenal reductase, and hexadecanal: NADP+ oxidoreductase.