2021 Australian Open – Wheelchair women's singles

Diede de Groot defeated the defending champion Yui Kamiji in the final, 6–3, 6–7^(4–7), 7–6^(10–4) to win the women's singles wheelchair tennis title at the 2021 Australian Open. It was the first step in an eventual Super Slam for de Groot.

Wheelchair women's singles
2021 Australian Open
Champion	Diede de Groot
Runner-up	Yui Kamiji
Score	6–3, 6–7(4–7), 7–6(10–4)
Draw	8
Seeds	2

Main article: 2021 Australian Open

Seeds

1. Diede de Groot (champion)
2. Yui Kamiji (final)

Draw

Key

• Q = Qualifier
• WC = Wild card
• LL = Lucky loser
• Alt = Alternate
• ITF = ITF entry
• PR = Protected ranking
• SR = Special ranking
• SE = Special exempt
• JE = Junior exempt
• JR = Junior Accelerator Programme entrant
• CO = College Accelerator Programme entrant
• NG = Next Gen Accelerator Program entrant
• w/o = Walkover
• r = Retired
• d = Defaulted

Bracket

	Quarterfinals							Semifinals							Final
	1	Diede de Groot	6	3	6
		Aniek van Koot	0	6	4
								1	Diede de Groot	6	6
									Momoko Ohtani	2	4
		Momoko Ohtani	6	6
		Lucy Shuker	2	2
															1	Diede de Groot	6	64	710
															2	Yui Kamiji	3	77	64
		Angélica Bernal	1	2
		Kgothatso Montjane	6	6
									Kgothatso Montjane	1	7	0
								2	Yui Kamiji	6	5	6
		Macarena Cabrillana	0	1
	2	Yui Kamiji	6	6