2022 Australian Open – Wheelchair women's singles

Defending champion Diede de Groot^[1] defeated Aniek van Koot in the final, 6–1, 6–1 to win the women's singles wheelchair tennis title at the 2022 Australian Open. It was the first step in an eventual Grand Slam for de Groot.

Main article: 2022 Australian Open

Wheelchair women's singles
2022 Australian Open
Champion	Diede de Groot
Runner-up	Aniek van Koot
Score	6–1, 6–1
Draw	8
Seeds	2

Seeds

1. Diede de Groot (champion)
2. Yui Kamiji (quarterfinals)

Draw

Key

• Q = Qualifier
• WC = Wild card
• LL = Lucky loser
• Alt = Alternate
• ITF = ITF entry
• PR = Protected ranking
• SR = Special ranking
• SE = Special exempt
• JE = Junior exempt
• JR = Junior Accelerator Programme entrant
• CO = College Accelerator Programme entrant
• NG = Next Gen Accelerator Program entrant
• w/o = Walkover
• r = Retired
• d = Defaulted

Bracket

	Quarterfinals							Semifinals							Final
	1	Diede de Groot	6	6
		Dana Mathewson	2	1
								1	Diede de Groot	6	7
								WC	Lucy Shuker	0	5
		Zhu Zhenzhen	2	2
	WC	Lucy Shuker	6	6
															1	Diede de Groot	6	6
																Aniek van Koot	1	1
		Kgothatso Montjane	6	64	7
		Jiske Griffioen	1	77	5
									Kgothatso Montjane	3	4
									Aniek van Koot	6	6
		Aniek van Koot	7	7
	2	Yui Kamiji	5	5