23S rRNA (adenosine1067-2'-O)-methyltransferase

23S rRNA (adenosine¹⁰⁶⁷-2'-O)-methyltransferase (EC 2.1.1.230, 23S rRNA A1067 2'-methyltransferase, thiostrepton-resistance methylase, nosiheptide-resistance methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenosine¹⁰⁶⁷-2'-O)-methyltransferase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenosine¹⁰⁶⁷ in 23S rRNA ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + 2'-O-methyladenosine¹⁰⁶⁷ in 23S rRNA

23S rRNA (adenosine1067-2'-O)-methyltransferase
Identifiers
EC no.	2.1.1.230
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus.