3-Methyl-PCPy

3-Methyl-PCPy (3-Me-PCPy) is an arylcyclohexylamine derivative with an unusual spectrum of pharmacological effects, acting as both a potent NMDA antagonist and also a triple reuptake inhibitor which inhibits reuptake of all three monoamine neurotransmitters serotonin, dopamine and noradrenaline. It also acts as a high affinity sigma receptor ligand, selective for the σ₂ subtype. It produces both stimulant and dissociative effects in animal behavioural studies.^[1][2][3]

3-Me-PCPy

Clinical data
ATC code	None
Legal status
Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name 1-[1-(3-methylphenyl)cyclohexyl]pyrrolidine
CAS Number	1622348-63-3 Y
PubChem CID	137332188
ChemSpider	129433265
UNII	FS9Z5C7CQ5
CompTox Dashboard (EPA)	DTXSID201337066
Chemical and physical data
Formula	C17H25N
Molar mass	243.394 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=CC(=CC=C1)C2(CCCCC2)N3CCCC3
InChI InChI=1S/C17H25N/c1-15-8-7-9-16(14-15)17(10-3-2-4-11-17)18-12-5-6-13-18/h7-9,14H,2-6,10-13H2,1H3 Key:JZVMREFYFTZXGN-UHFFFAOYSA-N

Legal Status

3-Methyl-PCPy is covered by drug analogue laws in various jurisdictions (UK, Germany, Japan, Australia etc.) as a generic arylcyclohexylamine derivative, and a structural isomer of phencyclidine.

See also

• 3-Methyl-PCP
• BTCP
• Deoxymethoxetamine
• Ephenidine
• MDPCP