3-deoxy-D-manno-octulosonate aldolase

The enzyme 3-deoxy-D-manno-octulosonate aldolase (EC 4.1.2.23) catalyzes the chemical reaction

3-deoxy-D-manno-octulosonate ${\displaystyle \rightleftharpoons }$ pyruvate + D-arabinose

3-deoxy-D-manno-octulosonate aldolase
Identifiers
EC no.	4.1.2.23
CAS no.	9026-95-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxyoctonate aldolase, KDOaldolase, 3-deoxyoctulosonic aldolase, 2-keto-3-deoxyoctonic aldolase, 3-deoxy-D-manno-octulosonic aldolase, and 3-deoxy-D-manno-octulosonate D-arabinose-lyase.