4-AcO-MPT

4-AcO-MPT, also known as 4-acetoxy-N-methyl-N-propyltryptamine, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to 4-AcO-DMT (psilacetin).^{[1][2][3][4][5]} It is thought to act as a prodrug of 4-HO-MPT and hence is believed to act as a non-selective serotonin receptor agonist including of the serotonin 5-HT_2A receptor.^[3][4] The drug produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents,^[4] and was first encountered as a novel designer drug in 2018.^[1] 4-AcO-MPT was first described in the scientific literature by at least 2017.^[2]

4-AcO-MPT

Clinical data
Other names	4-Acetoxy-MPT; 4-Acetoxy-N-methyl-N-propyltryptamine
Routes of administration	Oral
Drug class	Non-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code	None
Identifiers
IUPAC name [3-[2-[methyl(propyl)amino]ethyl]-1H-indol-4-yl] acetate
CAS Number	2173386-55-3
PubChem CID	140837843
ChemSpider	84400425
UNII	D28FL93BLV
Chemical and physical data
Formula	C16H22N2O2
Molar mass	274.364 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCN(C)CCC1=CNC2=C1C(=CC=C2)OC(=O)C
InChI InChI=1S/C16H22N2O2/c1-4-9-18(3)10-8-13-11-17-14-6-5-7-15(16(13)14)20-12(2)19/h5-7,11,17H,4,8-10H2,1-3H3 Key:CECCEKYTLKWWJJ-UHFFFAOYSA-N

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Chemistry

Analogues

Analogues of 4-AcO-MPT include methylpropyltryptamine (MPT), 4-HO-MPT (meprocin), 5-MeO-MPT, 4-AcO-DMT (psilacetin), 4-AcO-MET (metacetin), 4-AcO-MiPT (mipracetin), and 4-AcO-DPT (depracetin), among others.

See also

• Substituted tryptamine