4-hydroxybenzoate decarboxylase

The enzyme 4-hydroxybenzoate decarboxylase (EC 4.1.1.61) catalyzes the chemical reaction

4-hydroxybenzoate ${\displaystyle \rightleftharpoons }$ phenol + CO₂

4-hydroxybenzoate decarboxylase
Identifiers
EC no.	4.1.1.61
CAS no.	37290-53-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxybenzoate carboxy-lyase (phenol-forming). Other names in common use include p-hydroxybenzoate decarboxylase, and 4-hydroxybenzoate carboxy-lyase. This enzyme participates in benzoate degradation via CoA ligation.