4-Hydroxybenzoate geranyltransferase

4-hydroxybenzoate geranyltransferase (EC 2.5.1.93, PGT1, PGT2, 4HB geranyltransferase, 4HB:geranyltransferase, p-hydroxybenzoate geranyltransferase, PHB geranyltransferase, geranyl diphosphate:4-hydroxybenzoate geranyltransferase) is an enzyme with systematic name geranyl-diphosphate:4-hydroxybenzoate 3-geranyltransferase.^[1][2][3] This enzyme catalyses the following chemical reaction

geranyl diphosphate + 4-hydroxybenzoate ${\displaystyle \rightleftharpoons }$ 3-geranyl-4-hydroxybenzoate + diphosphate

4-hydroxybenzoate geranyltransferase
Identifiers
EC no.	2.5.1.93
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme is involved in shikonin biosynthesis. It has a strict substrate specificity for geranyl diphosphate and an absolute requirement for Mg²⁺.