4-hydroxyphenylacetate decarboxylase

The enzyme 4-hydroxyphenylacetate decarboxylase (EC 4.1.1.83) catalyzes the chemical reaction

(4-hydroxyphenyl)acetate + H⁺ ${\displaystyle \rightleftharpoons }$ 4-methylphenol + CO₂

4-hydroxyphenylacetate decarboxylase
Identifiers
EC no.	4.1.1.83
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming). Other names in common use include p-hydroxyphenylacetate decarboxylase, p-Hpd, 4-Hpd, and 4-hydroxyphenylacetate carboxy-lyase.