4-phosphopantoate—beta-alanine ligase

4-Phosphopantoate—β-alanine ligase (EC 6.3.2.36, phosphopantothenate synthetase, TK1686 protein) is an enzyme with systematic name (R)-4-phosphopantoate:beta-alanine ligase (AMP-forming).^[1] This enzyme catalyses the following chemical reaction

ATP + (R)-4-phosphopantoate + β-alanine ${\displaystyle \rightleftharpoons }$ AMP + diphosphate + (R)-4'-phosphopantothenate

4-Phosphopantoate—β-alanine ligase
Identifiers
EC no.	6.3.2.36
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part of the pathway leading to biosynthesis of 4'-phosphopantetheine.