5-aminovalerate transaminase

In enzymology, a 5-aminovalerate transaminase (EC 2.6.1.48) is an enzyme that catalyzes the chemical reaction

5-aminopentanoate + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ 5-oxopentanoate + L-glutamate

5-aminovalerate transaminase
Identifiers
EC no.	2.6.1.48
CAS no.	37277-97-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are 5-aminopentanoate and 2-oxoglutarate, whereas its two products are 5-oxopentanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 5-aminopentanoate:2-oxoglutarate aminotransferase. Other names in common use include 5-aminovalerate aminotransferase, delta-aminovalerate aminotransferase, and delta-aminovalerate transaminase. This enzyme participates in lysine degradation. It employs one cofactor, pyridoxal phosphate.