Aleph-6

Aleph-6, or ALEPH-6, also known as 4-phenylthio-2,5-dimethoxyamphetamine, is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.^[1][2][3] It is one of the Aleph series of compounds.^[1][2][3] In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists Aleph-6's dose as greater than 40 mg orally and its duration as "probably long".^[1][2][3] The effects of Aleph-6 have been reported to include "un-worldliness", among others.^[1] It was reported to have synergized with LSD when taken in combination with it.^[1] Overall however, Shulgin regarded Aleph-6 as a "disappointment" and that it may be a "forever threshold thing".^[1] The chemical synthesis of Aleph-6 has been described.^[1][2] The 2C analogue, 2C-T-6, has never been synthesized.^[1] Aleph-6 was first described in the literature by Shulgin in PiHKAL in 1991.^[1][2][3]

Aleph-6

Clinical data
Other names	ALEPH-6; DOT-6; 4-Phenylthio-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-4-phenylthioamphetamine; 4-PhS-DMA
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Pharmacokinetic data
Duration of action	"Probably long" (at least 12 hours)[1]
Identifiers
IUPAC name 1-(2,5-dimethoxy-4-phenylsulfanylphenyl)propan-2-amine
CAS Number	952006-44-9
PubChem CID	44719475
ChemSpider	23552980
UNII	3961V7J60A
CompTox Dashboard (EPA)	DTXSID501024775
Chemical and physical data
Formula	C17H21NO2S
Molar mass	303.42 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC1=CC(=C(C=C1OC)SC2=CC=CC=C2)OC)N
InChI InChI=1S/C17H21NO2S/c1-12(18)9-13-10-16(20-3)17(11-15(13)19-2)21-14-7-5-4-6-8-14/h4-8,10-12H,9,18H2,1-3H3 Key:CSOTVYXYZSJOFL-UHFFFAOYSA-N

See also

• DOx (psychedelics)
• Aleph (psychedelics)