ALPHA (drug)

ALPHA, also known as 3,4-methylenedioxy-α-ethylbenzylamine, is a psychoactive drug of the substituted benzylamine group and a positional isomer of 3,4-methylenedioxyamphetamine (MDA).^[1][2] It is also a benzylamine analogue of 3,4-methylenedioxyamphetamine (MDA).^[1][2] ALPHA was first synthesized by Alexander Shulgin.^[1][2] In his book PIHKAL on the MDA page, the threshold dosage is listed as 10 mg.^[1] At mild threshold dosages (around 10 mg) there are eyes-closed "dreams" with some body tingling, at higher doses (up to 140 mg) was reported to produce a pleasant, positive feeling.^[1] This compound is not anoretic at any dose.^[1] Its duration is about 3 hours.^[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of ALPHA.^[1][2] The drug was encountered as a novel designer drug by 1996.^[3][4]

ALPHA

Clinical data
Other names	3,4-Methylenedioxy-α-ethylbenzylamine; 1-Amino-1-(3,4-methylenedioxyphenyl)propane
Routes of administration	Oral[1]
Drug class	Unknown[1]
ATC code	None
Pharmacokinetic data
Duration of action	~3 hours[1]
Identifiers
IUPAC name 1-(1,3-Benzodioxol-5-yl)propan-1-amine
CAS Number	127292-42-6 Y
PubChem CID	14647596
ChemSpider	11853242 Y
UNII	AC10C1L8VO
CompTox Dashboard (EPA)	DTXSID701027199 DTXSID70562589, DTXSID701027199
Chemical and physical data
Formula	C10H13NO2
Molar mass	179.219 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(N)c1ccc2OCOc2c1
InChI InChI=1S/C10H13NO2/c1-2-8(11)7-3-4-9-10(5-7)13-6-12-9/h3-5,8H,2,6,11H2,1H3 Y Key:VEOUOCLRLNJOLJ-UHFFFAOYSA-N Y
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See also

• M-ALPHA (N-methyl analogue)
• MDM1EA (3,4-methylenedioxy-α,N-dimethylbenzylamine)
• Methylenedioxybenzylpiperazine (MDBZP)
• Homo-MDA
• Homo-MDMA
• Indanorex