ATP diphosphatase

In enzymology, an ATP diphosphatase (EC 3.6.1.8) is an enzyme that catalyzes the chemical reaction

ATP + H₂O ${\displaystyle \rightleftharpoons }$ AMP + diphosphate

ATP diphosphatase
Identifiers
EC no.	3.6.1.8
CAS no.	37289-25-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are AMP and diphosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is ATP diphosphohydrolase (diphosphate-forming). Other names in common use include ATPase, ATP pyrophosphatase, adenosine triphosphate pyrophosphatase, and ATP diphosphohydrolase [ambiguous]. This enzyme participates in purine metabolism and pyrimidine metabolism.