Acetylenedicarboxylate decarboxylase

The enzyme acetylenedicarboxylate decarboxylase (EC 4.1.1.78) catalyzes the chemical reaction

acetylenedicarboxylate + H₂O ${\displaystyle \rightleftharpoons }$ pyruvate + CO₂

Acetylenedicarboxylate decarboxylase
Identifiers
EC no.	4.1.1.78
CAS no.	72561-10-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.