Adenosylcobinamide hydrolase

In enzymology, an adenosylcobinamide hydrolase (EC 3.5.1.90) is an enzyme that catalyzes the chemical reaction

adenosylcobinamide + H₂O ${\displaystyle \rightleftharpoons }$ adenosylcobyric acid + (R)-1-aminopropan-2-ol

adenosylcobinamide hydrolase
Identifiers
EC no.	3.5.1.90
CAS no.	905988-16-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are adenosylcobinamide and H₂O, whereas its two products are adenosylcobyric acid and (R)-1-aminopropan-2-ol.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is adenosylcobinamide amidohydrolase. Other names in common use include CbiZ, and AdoCbi amidohydrolase. This enzyme participates in porphyrin and chlorophyll metabolism.