Α-Cadinol

α-Cadinol or 10α-hydroxy-4-cadinene is an organic compound, a sesquiterpenoid alcohol.^[1][2]

α-Cadinol

Names
IUPAC name Cadin-4-en-10-ol
Systematic IUPAC name (1R,4S,4aR,8aR)-1,6-Dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol
Identifiers
CAS Number	481-34-5 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:132905 Y
ChemSpider	8574094
PubChem CID	10398656
UNII	DC0YJ4816P Y
CompTox Dashboard (EPA)	DTXSID701017679
InChI InChI=1S/C15H26O/c1-10(2)12-7-8-15(4,16)14-6-5-11(3)9-13(12)14/h9-10,12-14,16H,5-8H2,1-4H3/t12-,13-,14+,15+/m0/s1 Key: LHYHMMRYTDARSZ-BYNSBNAKSA-N InChI=1/C15H26O/c1-10(2)12-7-8-15(4,16)14-6-5-11(3)9-13(12)14/h9-10,12-14,16H,5-8H2,1-4H3/t12-,13-,14+,15+/m0/s1 Key: LHYHMMRYTDARSZ-BYNSBNAKBA
SMILES CC1=C[C@H]2[C@@H](CC[C@@]([C@@H]2CC1)(C)O)C(C)C
Properties
Chemical formula	C 15H 26O
Molar mass	222.37 g/mol
Appearance	white crystalline
Melting point	73 to 74 °C (163 to 165 °F; 346 to 347 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Natural occurrence

This compound is found in essential oils and extracts of many plants, such as

• Agrotaxis selaginoides,
• Tabernaemontana catharinensis^[3]
• Litsea acutivena (7.7%),^[4]
• Salvia aratocensis (20%),^[5]
• Protium giganteum (7%),^[6]
• Uvaria ovata root bark (13–24%),^[7]
• Plinia trunciflora (19%)^[8]
• Tanacetum sonbolii (35%)^[9]
• Schisandra chinensis berries (5%),^[10]
• Melia azedarach (11%),^[11]
• Neolitsea parvigemma (10%),^[12]
• Tetradenia riparia (8%)^[13]

Biological activity

α-Cadinol was said to act as anti-fungal^[12] and as hepatoprotective,^[14] and was proposed as a possible remedy for drug-resistant tuberculosis.^[5]

See also

• δ-Cadinol (torreyol)