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Arsenite-transporting ATPase

Class of enzymes From Wikipedia, the free encyclopedia

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In enzymology, an arsenite-transporting ATPase (EC 3.6.3.16) is an enzyme that catalyzes the chemical reaction

ATP + H2O + arsenitein ADP + phosphate + arseniteout

The 3 substrates of this enzyme are ATP, H2O, and arsenite, whereas its 3 products are ADP, phosphate, and arsenite.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (arsenite-exporting).

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Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1IHU, 1II0, and 1II9.

See also

References

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