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Beatrice (drug)
Psychedelic drug From Wikipedia, the free encyclopedia
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Beatrice, also known as 4-methyl-2,5-dimethoxy-N-methylamphetamine or as N-methyl-DOM, MDOM, or MDO-D, is a lesser-known psychoactive drug of the phenethylamine, amphetamine, and DOx families.[1][2] It is a substituted methamphetamine and a homolog of 2,5-dimethoxy-4-methylamphetamine (DOM).[1][2] Beatrice was first synthesized by Alexander Shulgin.[1][2]
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Use and effects
In Shulgin's book PiHKAL, the minimum dosage is listed as 30 mg, and the duration is listed as 6 to 10 hours.[1][2] Beatrice produces a vague feeling of openness and receptiveness, and causes a stimulative effect.[1] It also causes diarrhea.[1]
Pharmacology
Beatrice shows affinity for serotonin receptors.[3][4] Its affinities (Ki) were 415 nM for the 5-HT2 receptor and 3,870 nM for the 5-HT1 receptor.[3][4] The affinity of Beatrice for the serotonin 5-HT2 receptor was about 4-fold lower than that of DOM.[3][4] Functional activities were not reported.[3][4]
Beatrice substituted for DOM in rodent drug discrimination tests, albeit with relatively low potency.[5]
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Analogues
Analogues of Beatrice include N-methyl-DOET, N-methyl-DOI (N-Me-DOI), N-methyl-DOB, and IDNNA (N,N-dimethyl-DOI).[1][2][6][7] N-Methyl-DOI is a potent agonist of the serotonin 5-HT2A receptor similarly to DOI, but with several-fold reduced potency and slightly reduced efficacy.[7]
Society and culture
Legal status
In the United States, Beatrice is a Schedule I isomer of DOET.
See also
References
External links
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