Butyrate—acetoacetate CoA-transferase

In enzymology, a butyrate-acetoacetate CoA-transferase (EC 2.8.3.9) is an enzyme that catalyzes the chemical reaction

butanoyl-CoA + acetoacetate ${\displaystyle \rightleftharpoons }$ butanoate + acetoacetyl-CoA

butyrate-acetoacetate CoA-transferase
Identifiers
EC no.	2.8.3.9
CAS no.	66231-37-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are butanoyl-CoA and acetoacetate, whereas its two products are butanoate and acetoacetyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is butanoyl-CoA:acetoacetate CoA-transferase. Other names in common use include butyryl coenzyme A-acetoacetate coenzyme A-transferase, and butyryl-CoA-acetoacetate CoA-transferase.