Anisindione

Anisindione (brand name Miradon) is a synthetic anticoagulant and an 1,3-indandione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.^[1]

Anisindione

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name 2-(4-methoxyphenyl)indene-1,3-dione
CAS Number	117-37-3 Y
PubChem CID	2197
IUPHAR/BPS	6960
DrugBank	DB01125 Y
ChemSpider	2112 Y
UNII	S747T1ERAJ
KEGG	D07457 Y
ChEBI	CHEBI:133809 Y
ChEMBL	ChEMBL712 Y
CompTox Dashboard (EPA)	DTXSID3022611
ECHA InfoCard	100.003.806
Chemical and physical data
Formula	C16H12O3
Molar mass	252.269 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2c1ccccc1C(=O)C2c3ccc(OC)cc3
InChI InChI=1S/C16H12O3/c1-19-11-8-6-10(7-9-11)14-15(17)12-4-2-3-5-13(12)16(14)18/h2-9,14H,1H3 Y Key:XRCFXMGQEVUZFC-UHFFFAOYSA-N Y
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